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Antibiotics and antimicrobial therapy
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Clinical Microbiology and Antimicrobial Chemotherapy - Official IACMAC Journal
Conferences, Seminars and Workshops

IACMAC activity plan for 2018-2019

  • Research and Practice Seminar “Relevant aspects of antibiotics susceptibility detection” (February 19-22, 2019, Smolensk)
  • VII South-Russian Conference on Antimicrobial Therapy (March 28–29, 2019, Krasnodar)
  • XXI International Congress “Antimicrobial Therapy” (May 22–24, 2019, Moscow)
  • Russian-Chinese Congress on Antimicrobial Therapy and Clinical Microbiology (October 17–18, 2019, Ufa)

Online course “Antimicrobial Stewardship: Managing Antibiotic Resistance”

You are invited to participate in Massive Open Online Course (MOOC) in Russian. This educational course was developed by Dundee University, the British Society for Antimicrobial Chemotherapy (BSAC) and the Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC).

IACMAC Educational Program
  • The National educational program “Diagnostics, treatment and prevention of infectious diseases caused by multidrug resistant microorganisms. Nosocomial infectious diseases” (1 session)
  • The National educational program “Diagnostics, treatment and prevention of infectious diseases caused by multidrug resistant microorganisms. Community-acquired infectious diseases” (2 session)

Dear colleagues! We encourage to take part in multicenter prospective microbiological study of the antimicrobial resistance of community-acquired pathogens: S. pneumoniae, H. influenzae and S. pyogenes (PeGAS study).

Since 2015 IAC and IACMAC have conducted multicenter study aimed to evaluate the prevalence of mutation resistance to macrolide antibiotic in Mycoplasma pneumonia and Mycoplasma genitalium.

Website News

European Committee on Antimicrobial Susceptibility Testing (EUCAST) has amended the clinical classification of susceptibility (categories S,I and R): currently the clinical evaluation of susceptibility is connected with drug exposure in the nidus of infection.

The occupational standard on specialty "Medical microbiology" from the Ministry of Healthcare of the Russian Federation is posted on IACMAC website.

Clinical Microbiology and Antimicrobial Chemotherapy vol. 20, №3 is posted on the website.

Clinical guidelines on diagnostics and treatment of community-acquired pneumonia in adults.

The Russian Respiratory Society (RRC) and the Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC) have published for discussion the clinical guidelines on diagnostics and treatment of community-acquired pneumonia in adults.

Clinical guidelines “Mucoviscidosis: microbiological diagnostics of chronic respiratory infection”

Clinical guidelines on antimicrobial susceptibility testing, approved at the IACMAC extended session in Moscow are posted on the website.

Clinical guidelines on isolation, identification and antimicrobial susceptibility of Helicobacter pylori are added.

New Articles
Site News

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

“Strep throat” is highly prevalent among children, yet it is unknown why only some children develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into this classic childhood disease, we performed phenotypic, genotypic, and functional studies on pediatric group A Streptococcus (GAS) RT and non-RT tonsils from two independent cohorts.
Feb 14, 2019 - 14:20
Read more... :: Reads: 12
Site News

Spero Therapeutics Announces FDA Acceptance of IND Application for SPR994

Spero Therapeutics, Inc., a multi-asset clinical-stage biopharmaceutical company focused on identifying, developing and commercializing treatments in high unmet need areas involving multi-drug resistant (MDR) bacterial infections, today announced the acceptance by the FDA of its Investigational New Drug (IND) application for SPR994, Spero’s lead product candidate designed to be the first oral carbapenem antibiotic, for the treatment of complicated urinary tract infections (cUTI).
Feb 12, 2019 - 11:45
Read more... :: Reads: 17
Site News

Vitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data from randomised controlled trials

Randomised controlled trials (RCTs) of vitamin D to prevent COPD exacerbations have yielded conflicting results. Individual participant data meta-analysis could identify factors that explain this variation.
Jan 28, 2019 - 14:10
Read more... :: Reads: 58
Site News

Effectiveness of the probiotic Streptococcus salivarius K12 for the treatment and/or prevention of sore throat: a systematic review

Streptococcus salivarius K12 (SsK12) appears safe and well-tolerated, however further RCTs are required to establish its role as a prophylactic therapy, particularly amongst patients experiencing frequent exacerbations of pharyngitis. In the acute setting, SsK12 is unlikely to be effective if given concurrently with antibiotics, however further RCTs should establish its role as an alternative to antibiotics in non-severe cases, or when prescribed post-antibiotic therapy for the prevention of disease recurrence and/or secondary infection.
Jan 24, 2019 - 14:20
Read more... :: Reads: 69
Site News

In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

Widespread antimicrobial resistance often limits the availability of therapeutic options to only a few last-resort drugs that are themselves challenged by emerging resistance and adverse side effects. Apramycin, an aminoglycoside antibiotic, has a unique chemical structure that evades almost all resistance mechanisms including the RNA methyltransferases frequently encountered in carbapenemase-producing clinical isolates.
Jan 23, 2019 - 12:15
Read more... :: Reads: 77
Site News

Non-steroids anti-inflammatory drugs and risk of peritonsillar abscess in pharyngitis: a French longitudinal study in primary care

The safety of non-steroids anti-inflammatory drugs (NSAIDs) in the context of pharyngitis is doubtful with contradictory results in the literature.
Jan 16, 2019 - 12:05
Read more... :: Reads: 81
Site News

Is Vitamin D Supplementation Effective in Prevention of Recurrent Urinary Tract Infections in the Pediatrics? A Randomized Triple-Masked Controlled Trial

This study aimed to evaluate the impact of Vitamin D supplementation on prevention of recurrent urinary tract infections (UTIs) in the pediatrics.
Jan 15, 2019 - 14:15
Read more... :: Reads: 92
Site News

Antibiotic resistance of Escherichia coli from outpatient urinary tract infection in women in six European countries including Russia

In the Northern Dimension Antibiotic Resistance Study Finland, Germany, Latvia, Poland, Russia and Sweden investigated the resistance levels of Escherichia coli (E. coli) isolated from urine of outpatient women (18-65 years) that had symptoms of uncomplicated UTI by collecting samples in each respective nation.
Jan 14, 2019 - 11:30
Read more... :: Reads: 89
Site News

Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia

We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries).
Jan 14, 2019 - 11:10
Read more... :: Reads: 87
Site News

Oral metronidazole use and risk of acute pancreatitis: a population-based case-control study

Oral metronidazole used in combined regimens for Helicobacter pylori eradication has been associated with an increased risk of acute pancreatitis; however, it is less clear whether a similar association exists for single-regimen metronidazole.
Jan 12, 2019 - 10:30
Read more... :: Reads: 90
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Institute of Antimicrobial Chemotherapy (IAC) Scientific Center of Monitoring Antimicrobial Resistance The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy Department of Clinical Pharmacology
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